Shortly before 10pm on police attended the scene of the crash on the Mitchell Highway at Wongarbon, about 20 kilometres south-east of Dubbo.

Police believe a Toyota HiLux utility being driven by a 35-year-old man, and with a 29-year-old passenger, lost control and rolled a number of times, before coming to rest.

A second vehicle, a Toyota Landcruiser utility driven by a 19-year-old man, hit the stationary vehicle.

MAP: The area where the crash occurred ...

Both men inside the first car died at the scene, while the driver of the second vehicle was uninjured.

The 19-year-old man was conveyed to hospital for mandatory drug and urine tests.

Officers from Orana Mid-Western Police District attended and are investigating the circumstances surrounding the crash.

The Mitchell Highway was closed in both directions between Dubbo and Geurie, but has since reopened.

A report will be prepared for the information of the Coroner.

Anyone with information about the crash, or who has dashcam vision, is urged to contact Crime Stoppers on 1800 333 000 or at www.nsw.crimestoppers.com.au.

Information is treated in strict confidence. The public is reminded not to report crime via NSW Police social media pages.