Central West residents have been told to brace for lockdown beyond September 10

Despite the announcement of a two-week extension to regional lockdown on Thursday, deputy premier John Barilaro told regional media there was "no way in the world" some communities would be able to come out of lockdown on September 10.

"For me, Dubbo and the Central West there, western NSW, I know we just talked about a two-week lockdown, but there's no way in the world they will be coming out in two weeks or four weeks," he said.

"I think Dubbo and that area is probably aligned with Sydney in a sense in relation to when we get to 70 per cent double dose and 80 per cent double dose and that's the truth of it because these numbers aren't budging and that's a tough situation to be in.

"My job is to make sure that doesn't escalate worse in that area, but also further escalate into other areas. It's a tough period for that community."

There were three new cases confirmed in Orange to 8pm on Wednesday, which took the Local Government Area's official total of active cases to 15. Six of those cases, though, have been sent back to Western Sydney.

Mr Barilaro said the regions do have the ability to "contain and supress" the virus so the health system isn't overwhelmed, but acknowledged there are challenges arising from community transmission and low testing numbers.

Dubbo continues to be one of the areas of greatest concern, with over 300 cases recorded to date.

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