Central West Police District acting inspector Wes Bush said the three people were in a Holden Commodore which hit a road hump at speed causing a front tyre to blow.

Acting Inspector Bush said the driver lost control of the car and it crashed into a Holden Commodore Ute at the intersection of Adina Crescent and Garema Road.

"The driver fled the scene. There were two other passengers in the car [who also left the scene]," he said.

He said the driver of the other car was not injured in the crash.

Acting Inspector Bush said the incident occurred at 3.30pm on Saturday.

He said the car had not been reported as stolen.

Police and an Orange Fire and Rescue crew attended the scene of the crash.

Acting Inspector Bush said police enquiries were continuing on Sunday to locate the driver.

Anyone with information should contact Orange Police or call Crime Stoppers on 1800 333 000.