A Fast Life On Wheels will have Ferguson use humour to tell his story, from the years as a member of the Doug Anthony All Stars to the progression of his Multiple Sclerosis.

"I'm aiming to bring a bit of Blayney civility to Bathurst and Orange," he said.

"Bathurst and Orange might have their cafes, but Blayney is content with their cups of tea and hot milk with Nescafe."

VIDEO: Tim Ferguson shares tips for life with multiple sclerosis ...

MS has confined Ferguson to a wheelchair for the past few years, but the comic legend said he uses his condition to empower people with a disability.

"It's important to give people with a disability the chance to enjoy the same quality of life as any other, and anyone who opposes the National Disability Insurance Scheme is a gormless gump," he said.

"Let's face it, all people have some form of disability, whether it be stupidity or, even worse, baldness and ugliness.

"It's inspiring to see so many stupid people move into roles such as politicians and bank managers."

Ferguson gave television viewers an insight into his shower routine in last year's Tick F***ing Tock, an ABC documentary on DAAS, to highlight the role of support workers.

"There's a lot of Australians who need help in the shower and while it seems confronting, you get used to it and support workers deserve a lot more recognition for their work," he said.

"I felt it would make for great television too, as people would get to see me naked."

The documentary also showcased the close connection between Ferguson and fellow DAAS members Paul McDermott, Richard Fidler and Paul 'Flacco' Livingston.

"When we first broke up, it was a stressful time for all of us, but we've always been great friends and it's important to show that south poles of magnets can live in the box together," he said.

Along with his comedic prowess, Ferguson is a well-revered screenwriter, director and producer, and owns the third-largest Star Wars collection in the southern hemisphere.

During his visit, he will host a comedy writing masterclass at Bathurst Library on September 29.

Ferguson said audiences can expect to walk away from the show with a positive outlook on life, no matter how bad it may be.

A Fast Life on Wheels is on at the Orange Civic Theatre on September 27.

Tickets are available via Serious Comedy.