Skye Payne and Aaliyah Ramage, both in Year 12 at Canobolas Rural Technology High School, went to Sydney on Sunday for the activities.

They will join about 200 girls and young women during NAIDOC Week for the event.

The Girls Academy Summit is organised by the Girls Academy, an in-school mentoring program for Aboriginal and Torres Strait Islander girls across Australia.

The students will meet and hear from guests including Dunghutti model Samantha Harris, Yolngu television presenter and producer Leila Gurruwiwi from the Marngrook Footy Show; CEO of the Australian Indigenous Governance Institute Michelle Deshong and NAIDOC's 2018 Youth of the Year Tamina Pitt.

It will include a careers expo which will feature employers and educational institutions. There will also be workshops and activities.

Aaliyah said she was looking forward to the activities.

"I am going on the high ropes course," she said.

Skye said she was keen on "meeting other girls from the different Girls Academies."

Canobolas High School's Girls Academy program manager Nikita Mason said the summit was open to Year 12 students.

She said there would be a range of events at the summit.

"It's all going to be a surprise when we get there," she said before leaving Orange on Sunday.