An aerial dump of 1080, the controversial bait which has been the subject of fierce campaigning by animal activists, will begin in Autumn on an area of public and private land twice the size of the drop the Central Tablelands did in the region in 2018.

Used to target wild dogs, Dr Brisbane said 1080 bait has posed a threat to pet dogs in the past and is almost always fatal when consumed.

She said in her 22 years at Canobolas Family Pet Hospital she has seen between 30-50 cases of dogs who have ingested the bait, but in recent years these incidents have ceased.

"It's a pretty horrific way for them to die. Initially there is vomiting, diarrhoea and abdominal discomfort and that leads to fits and seizures. It's a pretty nasty poisoning," she said.

Dr Brisbane said it is a quick and effective poison and the dogs which don't die on the way to the surgery are usually euthanised, so the best way to protect pets was to ensure they were secured in backyards and kept on leashes in areas where baiting took place.

While the exact location of the aerial baiting will not be decided until May, Central Tablelands Local Land Services, which will provide technical support for the program, has said it will be one of the largest wild dog-baiting programs, with up to 900 kilometres of aerial bait trails layed.

Dr Brisbane said she empathised with farmers who lost livestock to wild dogs and an alternative bait [Para-aminopropiophenone] was available which had an antidote to save pets.

LLS Team Leader for Invasive Species Tim Seears said at this point in time 1080 is the best option for poisoning wild dogs.

"1080 is used because it has a short life and breaks down with microbes in the soil. It's very target specific," he said. 

Mr Seears said poisons which are used overseas - such as cyanide in the US - are banned in Australia and the use of 1080 was highly regulated in the tablelands jurisdiction with strict guidelines regarding notification of its laying, public signage and mail outs.

LLS will work with Forestry Corporation NSW, the National Parks and Wildlife Service and Crown Lands agencies for the baiting program.