Men's 100m freestyle
James Magnussen, Australia's best medal chance in the pool, is talking up a world record and it wouldn't be a successful Olympics effort without one.
Women's 100m hurdles
Reigning world champion Sally Pearson went into the last Games with no expectations but enters London with the eyes of the world on her.
The 28-year-old cyclist won gold and bronze in Athens before a horror accident meant she almost missed Beijing. She took silver there and is now a medal chance in the keirin and individual sprint.
The Kookaburras are the world champions and took bronze in Beijing. They don't want to finish bridesmaids again.
The swimmer won three gold medals at the Beijing Olympics but has since suffered a shoulder injury. All eyes will be on her in the women's 400m individual medley and 200m individual medley.
Michael Phelps v Ryan Lochte
Phelps won eight swimming gold medals in Beijing but his compatriot Lochte is determined to beat him in the men's 200m and 400m individual medley events.
The men's 100m sprint will be the highlight of the Games. The Jamaican hasn't come close to the 9.58-second world record he set at the 2009 world championships, but expect something special.
The Dream Team
Any game the US men's basketball team is in will be worth 10 times the price of admission. Similarities have been drawn between the present team and Michael Jordan's 1992 Olympic team, which won all six of its games by an average of 43 points.
At the past three Olympics, the finals have been contested by the US and Australia. This year, the Opals have a real chance of upsetting the US.
Other than the fact our very own Lauren Mitchell is a real medal chance, gymnastics has produced some of the greatest Olympic moments in history.
Games of the XXX Olympiad
Coverage begins Saturday on Nine and Foxtel